Product ID:DEPO-MEDROL STERILE AQUEOUS SUSPENSION
MSDS Date:01/01/1987
FSC:6505
NIIN:00-890-1186
MSDS Number: BWDZC

UPJOHN COMPANY, THE

7171 PORTAGE ROAD
KALAMAZOO, MI 49001
US

Emergency Phone: 616-323-6722 (24 HOURS)

Info Phone: 30 PM)

Cage: 93703

PHARMACIA & UPJOHN

KALAMAZOO, MI 49001-0199 US

Telephone: 616-833-5122/616-833-7555

Cage: 93703

WATER

CAS: 7732-18-5

RTECS: ZC0110000

Fraction By Weight: 88-94%

CARBOWAX POLYETHYLENE GLYCOL 3350

Fraction By Weight: 3%

METHYL PREDISOLONE ACETATE

CAS: 53-36-1

RTECS: TU4154050

Fraction By Weight: 2-8%

SODIUM CHLORIDE

CAS: 7647-14-5

RTECS: VZ4725000

Fraction By Weight: <1%

LD50 LC50 Mixture:ORAL LD50(RAT):>10G/KG,METHYLPREDISOLONE
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:METHYLPREDNISOLONE ACETATE AFFECTS
CARBOHYDRATE, PROTEIN AND FAT METABOLISM; FUNCTIONS OF THE
CARDIOVASCULAR SYSTEM, KIDNEY, SKELETAL MUSCLE, NERVOUS SYSTEM AND
OTHER ORGANS AND TISSUES. IT MAY MODIFY THE BODY'S IMMUNE RESPONSE
TO DIVERSE STIMULI. CHRONIC: MAY PRODUCE PITUITARY-ADRENAL
SUPPRESSION, CUSHING'S SYNDROME.
Effects of Overexposure:INCREASED SUSCEPTIBILTY TO INFECTIONS WITH
SUPPRESSION OF INFLAMMATORY RESPONSE, OSTEOPOROSIS, CATARACTS,
GLAUCOMA WITH POSSIBLE DAMAGE TO THE OPTIC NERVE, MENTAL SYMPTOMS,
HYPERGLYCEMIA AND GLYCOSURI A, MUSCULAR WEAKNESS AND FATIGUE,
ACNE,MENSTRUAL DISORDERS AND PEPTIC ULCERS.
Medical Cond Aggravated by Exposure:INCREASED SUSCEPTIBILITY TO
INFECTIONS.RECENT IMMUNIZATION PROCEDURES MAY RESULT IN A LACK OF
ANTIBODY RESPONSE AND NEUROLOGICAL DISORDERS.

First Aid:EYES- FLUSH WITH WATER FOR 15 MINUTES. HOLD EYELIDS OPEN TO
ASSURE COMPLETE CONTACT WITH WATER. SKIN- WASH WITH SOAP AND
WATER. REMOVE CONTAMINATED CLOTHING. INHALATION- REMOVE FROM
EXPOSURE. INGES TION- CONTACT A PHYSICIAN OR POISON CONTRO CENTER.

Flash Point:NONFLAMMABLE
Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL, WATER.
Fire Fighting Procedures:WEAR A NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT WHEN FIGHTING FIRES. USE
WATER SPRAY TO COOL FIRE EXPOSED CONTAINERS.
Unusual Fire/Explosion Hazard:NONE

Spill Release Procedures:PROVIDE VENTILATION AND RESPIRATORY, SKIN AND
EYE PROTECTION TO PREVENT OVEREXPOSURE. KEEP PRODUCT OUT OF DRAINS,
PREVENT ENTRY TO SURFACE WATER, GROUNDWATER OR SOIL. SMALL SPILLS
SHOULD BE ABSORBED W ITH PAPER TOWELS OR APPROPRIATE MEDIA.

Handling and Storage Precautions:AVOID CONTACT WITH SKIN, EYES AND
CLOTHING. WASH THROUGHLY AFTER HANDLING. LAUNDER CONTAMINATED
CLOTHES BEFORE REUSE. KEEP OUT OF REACH OF CHILDREN.
Other Precautions:NONE

Respiratory Protection:NONE NORMALLY REQUIRED.
Ventilation:LOCAL EXHAUST.
Protective Gloves:RUBBER
Eye Protection:SAFETY GLASSES WITH SIDE SHIELDS.
Other Protective Equipment:NONE
Work Hygienic Practices:WASH HANDS THOROUGHLY AFTER HANDLING THIS
MATERIAL.
Supplemental Safety and Health

HCC:N1
Appearance and Odor:LIQUID IN 1-, 5- OR 10-ML VIALS.

Stability Indicator/Materials to Avoid:YES
NONE
Stability Condition to Avoid:NONE
Hazardous Decomposition Products:CARBON DIOXIDE AND CARBON MONOXIDE.

Waste Disposal Methods:DISPOSE IN ACCORDANCE WITH FEDERAL, STATE AND
LOCAL REGULATIONS.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.